6 30 Pm Cdt (2024)

FAQs

How do you pass a CDT blood test? ›

The only way to guarantee that you will pass a DVLA CDT test is to abstain from drinking alcohol in the four weeks prior to taking the test.

The normal value of the serum CDT concentration is under 60 mg/liter; a value between 60 and 100 mg/liter indicates probable alcoholism, and a value > 100 mg/liter indicates a very high probability of alcoholism (specificity: 99%).

According to a publication available from the National Institute of Alcohol Abuse and Alcoholism CDT levels appear to elevate after consuming 60-80 grams of alcohol per day (approximately 4 to 6 440ml cans of fosters) for a period of 2 or 3 weeks and CDT levels will normalize with a mean half-life of 2 to 4 weeks ...

Transferrin remains in the circulation for 7 to 14 days and CDT, therefore, can give an indication of alcohol consumption over this period of time, which gives it an advantage over blood or urine alcohol measurements which only remain elevated for 24-48 hours after alcohol consumption.

In general, heavy alcohol consumption (50–80 g/day) for a period of at least 1 week leads to increased concentrations of CDT in serum; after abstinence, CDT returns to a normal level, with a half-life of 14 days.

CDT is reported as a percentage of total transferrin to reduce the effects of gender and varying transferrin concentrations. CDT has a long half-life of 15 days. Under conditions of total abstinence it may take 1-2 months for CDT levels to return to normal.

Samples are sent to a referral laboratory for analysis with results expected back within 3 weeks.

A The minimum scale score is 400, and the maximum scale score is 2000 for all CDT assessments.

Patients with chronic alcoholism may develop abnormally glycosylated transferrin isoforms (ie, carbohydrate deficient transferrin: CDT >0.12). CDT results from 0.11 to 0.12 are considered indeterminate. Patients with liver disease due to genetic or nongenetic causes may also have abnormal results.

If a person stops drinking, their CDT levels will usually return to normal levels within four weeks.

What happens if I fail the CDT test? ›

Consequences of Elevated Levels: If someone has failed the DVLA CDT test, they may face driving restrictions, mandatory rehabilitation programs, or retests before their driving privileges are restored. Reapplication: After facing a ban due to elevated CDT levels, individuals can reapply for their driving license.

In all patients, elevated CDT levels were found that significantly (p < 0.0001) decreased with the therapeutic diet (27.3 ± 11.5% versus 9.3 ± 5.1% for HFI and 43.8 ± 14.1% versus 11.2 ± 4.0% for galactosemia).

95% of non-drinkers and individuals with normal drinking patterns will have CDT values below 1.7%. Values greater than 1.7% usually indicate a consumption of more than 60 g of ethanol per day over a period of at least one week. Note that 5% of individuals will therefore have a %CDT of >1.7% without excessive drinking.

Over the years, studies have been carried out on various factors and substances that may affect the levels of CDT, among which are tobacco use. In fact, a further clinical application field of CDT is that in which it is used as marker of pathological conditions correlated or not to alcohol abuse.

In nonabusers, iron supplementation therapy significantly decreased CDT levels in patients with iron deficiency anemia (33.7 +/- 6.6 U/L vs. 21.7 +/- 5.2 U/L; P =. 0007), while iron-depletion treatment significantly increased CDT levels in patients with GH (9.7 +/- 2.0 U/L vs. 14.7 +/- 4.0 U/L; P =.

The CDT test can thus detect heavy alcohol consumption over a long period of time and is a measure of chronic alcohol consumption. If a person stops drinking, the CDT levels will return to normal levels within 4 weeks.

In alcoholic patients, CDT% results normalize within 2 weeks after cessation of drinking. This may pose a problem when alcoholics can choose to some extent when they provide a blood sample for follow-up, as they may reduce their drinking behavior in the weeks prior to sampling.

Consequences of Elevated Levels: If someone has failed the DVLA CDT test, they may face driving restrictions, mandatory rehabilitation programs, or retests before their driving privileges are restored. Reapplication: After facing a ban due to elevated CDT levels, individuals can reapply for their driving license.

The CDT level can become positive after two weeks of heavy drinking (defined as 60 grams or more of ethanol per day) and with abstinence the values normalize with a mean half-life of 14-17 days (Pharmacia, 1994). Thus a positive CDT can identify recent heavy drinking even after a person has stopped drinking.